ObjectiveTo evaluate the clinical effect of mild stimulation with letrozole on pregnancy outcomes in ovulatory women undergoing frozen embryo transfer (FET) compared to natural cycle. Letrozole is a selective and highly potent aromatase inhibitor that inhibits the enzyme activity of intracellular aromatase. Fertil Steril 2004;82:1561–3BackgroundThe long-term follow-up in children with familial male-limited precocious puberty (FMPP) who were treated with letrozole, triptorelin, and spironolactone is limited, especially considering the efficiency and safety. Femara induces ovulation in patients with polycystic ovary syndrome (PCOS), which is a condition where hormone imbalance can. 5 mg tablet administered once a. Advise pregnant women of the. The relative potential for letrozole, anastrozole, and fadrozole has been assessed in a range of cellular endocrine and tumor systems containing aromatase ( 6). 0) Unexplained: 34 (21. As stated in a 2004 report on the letrozole use in early-stage disease, extending adjuvant endocrine therapy with letrozole reduced breast cancer recurrences by 43 percent at a median follow-up of 2. Letrozole is Letrozole comes as tablets. In various studies reporting the use of letrozole for superovulation, letrozole was administered from cycle 3 to 7 with daily dose ranging from 2. Order Femara 2. 5. In Menopausal Women, the Ovaries do not produce Estrogen. Note: “During treatment” includes 30 days after last dose. 5mg. Risks. Peripheral oedema, chest pain. Belly pain. 2 Use of Lez-T and Food: The tablet can be taken with or without food. Clomid and Letrozole have emerged as go-to options for individuals seeking effective PCT strategies. It works by decreasing the amount of estrogen produced by the body. According to the latest guidelines, letrozole should be considered as the first-line pharmacological treatment for women with WHO Group II anovulation or PCOS. Femara is also used off-label (without FDA approval) as a fertility treatment. Letrozole is a generic drug also sold under the brand name Femara. Many clinics now prescribe Letrozole in place of Clomiphene Citrate (Clomid), which has been the standard. These are not all of the side effects that may occur. These are not all of the side effects that may occur. Letrozole dosage. found. In this population, 7 out of 9 and 7 out of 8 boys in the T + Lz and T + PlLetrozole Uses . 4 CONTRAINDICATIONS. siponimod and letrozole both increase immunosuppressive effects; risk of infection. Some of the most common ones include hot flashes, joint pain, fatigue, hair thinning, and nausea. It only works in women who are post-menopausal and producing estrogen outside the ovaries. 5 mg Tablets - NUTERENO HEALTH CARE You should only take Lez-T under strict medical supervision. 5 mg Tablet. One common side effect. 5) 0 (0. 21. Letrozole is a nonsteroidal inhibitor of aromatase which effectively blocks estrogen synthesis in postmenopausal women and is used as therapy of estrogen receptor positive breast cancer, usually after resection and after failure of tamoxifen. Letrozole should be taken anywhere from Day 2 to Day 5 of your menstrual cycle. 001). Skin-related adverse events associated with anastrozole inhibitor use are uncommon [3–18]. But this combination can potentially cause rare adverse effects in the body, including kidney toxicity [95]. 4. 5mg tablet is composed of Letrozole (2. Letrozole may be used with intracytoplasmic sperm injection cycles, particularly as a successful means of delivering in vitro fertilization care at an affordable price . You usually take letrozole once a day – try. Nausea. Letrozole comes in 2. 000 - R$8. What are the side effects to using letrozole? The use of letrozole is associated with many side effects, including an increase in cholesterol levels, a decrease in bone density, hot flashes, night sweats, nausea and vomiting, loss of appetite, constipation, diarrhea and heartburn, muscle and joint pain, fatigue and dizziness, swelling of. Letrozole, sold under the brand name Femara among others, is an aromatase inhibitor medication that is used in the treatment of breast cancer. The information provided in Name of the medicinal product of Cipla-Letrozole. 044) and a significant decrease in lumbar spine BMD (percentage change in T score, mean −0. And how long it takes for side effects to appear is different for every person. To use a strapless dildo, you or your partner need to have strong Kegels so that you can properly grip and hold onto the bulb end of the dildo. View uses, side effects, price in Pakistan and get expert advice. Adult: In hormone receptor +ve postmenopausal women: 2. 5 MG Tablet (30) online & get Flat 15% OFF on PharmEasy. In the extended adjuvant setting, the optimal treatment duration with letrozole tablets is not known. Methods: Adult heights and long-term follow-up data, including. 1 Adjuvant Treatment of Early Breast Cancer - Letrozole tablets are indicated for the adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer. Medicines, such as naproxen and ibuprofen, are available to help manage bone and joint pain. W 2. 16. severe and sudden, unexplained troubled breathing. 1. Letrozole caused embryo-fetal toxicities in rats and rabbits at maternal exposures that were below the maximum recommended human dose (MHRD) on a mg/m 2 basis. This product is available in the following dosage forms: Tablet; Before Using. Cases exposed to high dose letrozole 10 mg day −1 resulted in a higher ectopic pregnancy resolution rate of 85% (17/20), while the resolution rate of the low dose letrozole-treated group (5 mg day −1) was 65% (13/20), and also showed a significant reduction in β-hCG levels on the 11th day, 25. Usage Instructions for Letrozole; Take this drug at the same time of day. 688 of 1425 treatment cycles [48. Letrozole is also used to induce ovulation in women who exhibit polycystic ovary syndrome or anovulation. sudden speech problems. Early-stage, hormone receptor–positive (HR+) breast cancer that has been treated. Letrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body. Letrozole tablets may cause fetal harm when administered to a pregnant woman and the clinicl benefit to premenopausal women with breast cancer has not been demonstrated. The FDA approved its use in post menopausal women who show hormone receptor positive types of breast cancer. Letrozole Stada reduces the amount of estrogen by blocking an. Selet 2. 5 MG Tablet may cause side effects such as tiredness, loss of. It is a hormonal (or "endocrine") treatment for breast cancer. It works by keeping a certain hormone (estrogen) from stimulating the growth of breast cancer cells. The product code (s) for this leaflet is: PL 31750/0041 . 007). 008) at 24. . Hot flushes can sometimes occur. It can decrease the density of your bones and increase the chance of broken bones and fractures. Thus, letrozole was expected to have a potential of improving luteal function and outcome in patients with advanced maternal age. In single-dose studies, the highest dose used was 30 mg, which was well tolerated. This activity describes the indications, action, and contraindications for anastrozole as a valuable agent in managing advanced hormone-receptive breast cancer. This drug can also be used to prevent breast cancer from recurring. A drug with many uses. 5. Due to the promising preclinical and phase 1 results, and once again to shorten development. Although allergic reaction wasn’t reported in studies of Femara, it can still happen. The LTZ-FET protocol entailed 5 mg. In Menopausal Women, the Ovaries do not produce Estrogen. Tiredness and lack of energy may occur. A significantly greater number of participants receiving letrozole than those receiving placebo had a T score at the lumbar spine that was less than −2. Serum LH, FSH, total testosterone and inhibin-B were significantly higher after 6 months of use of letrozole in children with CDGP, when compared to those receiving placebo or testosterone. 0) Other: 5 (3. What is letrozole used for? Letrozole is used to treat breast cancer in women after menopause (change of life). These are not all of the side effects that may occur. Use of letrozole may cause decreases in bone mineral density (BMD). Casper says that about 1 percent of people who take letrozole get leg cramps and headaches, but the good news is that these symptoms go away once you stop. Letrozole inhibits the production of Estrogen and thus prevents the growth of a Tumor. It belongs to a group of medicines called aromatase inhibitors. 5. 5 Tablet is used in the treatment of Breast cancer,Infertility due to anovulation. Letrozole caused embryo-fetal toxicities in rats and rabbits at maternal exposures that were below the maximum recommended human dose (MHRD) on a mg/m 2 basis. comLetrozole is a medication used in the treatment of certain breast cancers. In 2020, it was the 257th most commonly prescribed medication in the United States, with more than 1 million prescriptions. The most common grade 3-4 adverse events in the ribociclib plus letrozole group were neutropenia (22 [43%] of 51 patients) and elevated alanine aminotransferase. Doctors usually recommend women to take around 2. 5 Tablet uses, side-effects, composition, substitutes, drug interactions, precautions, dosage, warnings only on Lybrate. It’s FDA-approved to treat certain types of breast cancer. Animals were randomly divided into two equal groups and subcutaneously received either 0. 3%) had hypoestrogenic. Avoid alcohol as it may make you feel more tired and drowsy. is based on data of another medicine with exactly the same composition as the Cipla-Letrozole. A previous study reported that the use of the natural cycles for timing FETs should be reserved for younger patients, probably because the luteal phase defects are more common in patients with advanced maternal age . Introduction In vitro fertilisation (IVF) is an effective infertility treatment but the live birth rate remains unsatisfactory. Letrozole 2. Consideration should be given to monitoring BMD. Letrozole is a third-generation aromatase inhibitor that is used mainly for the treatment of postmenopausal breast cancer. 35 for placebo and letrozole, respectively; P = . It prevents the recurrence of cancer. Consideration should be given to monitoring BMD. 3 Use in Extended Adjuvant Treatment of Early Breast Cancer. Complete Hemogram (CBC & ESR) Letzol 2. No experience with letrozole overdose has been reported. So, your ovaries produce more. In the clinical trial, called MONALEESA-2, women treated with the CDK4/6 inhibitor ribociclib (Kisqali) and the hormone-blocking drug letrozole (Femara) as their initial treatment for advanced breast cancer lived approximately 1 year longer overall than women treated with letrozole alone . Additionally, a study found that letrozole co-treatment could improve pregnancy outcomes by reversing the expression of anb3 integrin in the endometrium . The use of letrozole has recently attracted attention as an effective alternative to natural or HRT cycles in patients with ovulation disorders undergoing FET (Huang et al. Letrozole may cause other side effects. 5. Brand Name Price Savings;. The purpose of this paper is to. This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Got prescribed the letrozole on the smallest dose (2. In patients with advanced disease, treatment with Letrozole Tablet should be continued until tumor progression is evident. These side effects can often be managed with lifestyle changes. How it works Letrozole may be used to treat postmenopausal women whose cancers are fueled by hormones. to treat breast cancer in men and younger women. First-line treatments often include lifestyle changes, Clomid, letrozole, and metformin. In fact, with Clomid, having more than six cycles is discouraged (a max of three to four is recommended). Letrozole is an aromatase inhibitor used to treat breast cancer in postmenopausal women. Pain, redness/discolouration, heat and swelling of the arm or leg. Consult your doctor for more details. 2019, 112:371-7. In the MA. letrozole. Cypress: useful for circulation, can relieve stagnation associated with heavy bleeding or mid-cycle bleeding. In post-marketing reports, use of letrozole during pregnancy resulted in cases of spontaneous abortions and congenital birth defects. Letrozole decreases the amount of. The growth of breast tumors is often stimulated by the female sex hormone estrogen . You may report side effects to the FDA at 1-800-332-1088. to treat breast cancer in men and younger women. Estrogen hormone is important in a man; it plays a critical role in bone density, lipid metabolism, sexual maturation, and growth. It belongs to a group of medicines called aromatase inhibitors. Clomid stimulates the release of hormones. The GnRHa used for pre-HIFU treatment in group C patients can generate significantly more volume reduction of leiomyomas than letrozole used in group B patients (38. Letrozole के लाभ और उपयोग करने का तरीका - Letrozole Benefits & Uses in Hindi Letrozole इन बिमारियों के इलाज में काम आती है - Use of letrozole in CDGP was associated with a slower progression in BA when compared to those receiving placebo or testosterone. Introduction and background. Femara is. It is used for treating ERα-positive local or metastatic breast cancer in postmenopausal women. and R$3. Letrozole decreases the amount of estrogen. Elderly people (65 years of age and above) Patients 65 years of age and over can use Lez-T at the same dosage as other adults. This drug has been used for this purpose for decades and is still one of the few drugs that provide guaranteed results. Not able to sleep. Letrozole Bluefish belongs to a group of medicines called aromatase inhibitors. In their large 2017 study from Japan, Tatsumi et al. (AJOG, 2021) assessed the impact of letrozole (an aromatase inhibitor) during frozen embryo transfer (FET) on obstetrical and perinatal outcomes of singleton and twin pregnancies compared with artificial cycle FET among women with polycystic ovary syndrome METHODS: Retrospective cohort study Participants Women with PCOS undergoing FET from 2010 to […] pain in the chest, groin, or legs, especially the calves. 5. tablet that you swallow. Leave letrozole in the provided packaging until it is ready to be taken. 5mg letrozole for improving fertility. 1 Bone Effects. Indications and Dosage. It belongs to a group of medicines called aromatase inhibitors. ( 1. Letrozole is usually well-tolerated and serious side effects are rare. Letrozole comes as a tablet to take by mouth once a day with or without food. Femara is a drug. 5 mg once daily; continue until tumor progression. Effective use of letrozole for ovulation induction, in women with an inadequate response to CC, was first described by Mitwally and Casper in 2001. It resists the spread of cancer to other areas of the body. Nice, France, March 21–25 (2006) (Abstract 12). Learn about side effects, off-label use for infertility, and more. Letrozole is a highly effective aromatase inhibitor. 5 mg . , 2014 ), and no studies have investigated the. 2. 1 Bone Effects. 5 mg). Learn about side effects, off-label use for infertility, and more. Letrozole works by decreasing the amounts of these hormones in the body. It is used as the second treatment. For vaginal complaints such as dyspareunia, dryness and sexual dysfunction, topical estrogen may be considered. Letrozole as an aromatase inhibitor has been widely used in the treatment of female infertility [20–22]. 007). 1% taking tamoxifen; this was highly significant . These include diarrhea, belly pain, and nausea. Letrozole has an average rating of 5. The solution for oral inhalation is usually used. com. sudden loss of coordination. sudden loss of coordination. The recommended dose is one 2. Lez-T Letrozole 2. As a result, it can lower the rate of testosterone-to-estrogen conversion and estrone to androstenedione, decreasing the negative feedback on the hypothalamus through the inhibition of aromatization [26]. Letrozole is approved for use in the following clinical indications Adjuvant Treatment of Early Breast Cancer. An alternative schedule of extended adjuvant endocrine therapy with letrozole, including intermittent administration, might be feasible and the. Letrozole is an oral, anti-estrogen drug that is used for treating postmenopausal women with breast cancer. Results of a safety study to evaluate safety in the adjuvant setting comparing the effect on lumbar spine (L2 to L4) BMD of adjuvant treatment with letrozole to that with tamoxifen showed at 24 months a. 7 and −5. Lezra is used to treat postmenopausal breast cancer. Eat a bigger breakfast and a smaller dinner. Letrozole may be mainly used to treat breast cancer patients. Letrozole is in a class of medications called nonsteroidal aromatase inhibitors. Those receiving letrozole had a significantly greater decrease in total hip BMD (percentage change in T score, mean −0. Arimidex is sometimes taken to lower estrogen levels that are high due to anabolic steroid use. Letrozole works by lowering your estrogen levels which slows/reverses some cancers from growing. Alternate brands of Lezra tablet 2. This is not a complete list of side effects and others may occur. The text only version may be available in large print, Braille or audio CD . 5 MG Tablet is a medicine used in the treatment of breast cancer in postmenopausal women (women who have not had periods for more than a year marking the end of menstrual cycles). Letrozole Orion contains an active substance called letrozole. 5 MG: PRESCRIPTION REQUIRED: Mandatory: PRODUCT FORM: Tablet: ABOUT: Lezole 2. 60 for placebo and letrozole, respectively; P = . Results of a safety study to evaluate safety in the adjuvant setting comparing the effect on lumbar spine (L2 to L4) BMD of adjuvant treatment with letrozole to that with tamoxifen showed at 24 months a median. The aim of this study was to evaluate letrozole use on patients with normal menstrual cycles. Monitoring of cholesterol levels is necessary. sudden, severe weakness or numbness in the arm or leg. Letrozole is an aromatase inhibitor. 100% authentic medicine with nationwide delivery. 5 Laboratory Test Abnormalities No dose-related effect of letrozole on any hematologic or clinical chemistry parameter was evident. This is a decision. Use of letrozole may cause decreases in bone mineral density (BMD). It has been prescribed by fertility doctors since the early 2000s. After surgery, women who have hormone receptor positive breast cancer will have hormone therapy as part of their treatment. Clomid or letrozole is taken for 5 days, then stopped for 3 to 4 days. A total of 5,187 women participated in this study. Follicular development can be induced by the administration of letrozole via suppressing androgen conversion into oestradiol and increasing serum gonadotropin-releasing hormone levels []. Lesbian or single female: 7 (4. Use of letrozole may cause decreases in bone mineral density (BMD). Heart disease: This medication may increase the risk of heart attack or increased blood pressure. Letrozole is the most commonly used aromatase inhibitor for mild ovarian stimulation in ART (Requena et al. and R$50 - R$300 in Brazil. If tiredness is a problem, do not drive a car or operate machinery if you are feeling tired. Letrozole, also known by its brand name Femara, is an oral medication used to stimulate egg development and ovulation in female patients undergoing fertility treatment . Zhang J, Liu H, Wang Y, et al. (AJOG, 2021) assessed the impact of letrozole (an aromatase inhibitor) during frozen embryo transfer (FET) on obstetrical and perinatal outcomes of singleton and twin pregnancies compared with artificial cycle FET among women with polycystic ovary syndrome METHODS: Retrospective. Letrozole. According to the most recent research, letrozole can be used as the first-line therapy to treat infertility caused by polycystic ovarian syndrome and other causes. Filter by condition. Breast cancer that has gotten worse after antiestrogen therapy. The growth of some breast cancers in postmenopausal women is. 1 Bone Effects. LH levels were measured in week 5 before pellet removal (Pre) and in week 11 (Post). . Novartis had manufactured the drug after it was approved for sale on the American prescription drug market in 1997, and was sold as the brand name Femara as well as a separate brand name Femar in certain other select countries across the world (mostly in. 5 mg, taken cycle days 3-7). Therefore, letrozole treatment is considered an effective option in endometrial preparation for FET in patients with ovulation disorders or irregular menstruation. As breast tissue is stimulated by estrogens, decreasing their production is a way of suppressing recurrence. 4 years. Use of letrozole may cause decreases in bone mineral density (BMD). Hair loss. Pregnancy, breastfeeding, and fertility. Weight gain or loss. Some forms of cancer cells of breast that require estrogen to proliferate can be slowed or stopped by this. It reduces the amount of estrogen produced by the body. com. m. Letrozole may be used with intracytoplasmic sperm injection cycles, particularly as a successful means of delivering in vitro fertilization care at an affordable price . Letrozole Teva contains an active substance called letrozole. You may report side effects to the FDA at 1-800-332-1088. Increased hepatic enzymes, hyperbilirubinemia, jaundice. massage. Chris Li and others at the Hutch now suggests bisphosphonates may. Doctors usually recommend women to take around 2. Femara (letrozole) is indicated for the adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer. Letrozole is a nonsteroidal aromatase inhibitor that reversibly binds to aromatase enzyme, and inhibits estrogen synthesis. 1 Bone Effects. The Benefits of Using Letrozole for Pregnancy. Yellow skin and yellow whites of the eyes, nausea, decreased appetite, dark urine (signs of hepatitis ). Letrozole is an aromatase inhibitor indicated for: Adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer. Selet 2. Presented at: European Breast Cancer Conference 2006. For context, compared with IVF, IUI. 33) and natural cycle (OR 1. 0 tablets) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg. Early-stage breast cancer that has been treated with tamoxifen citrate for at least 5 years. m. When the enzyme. This decrease in estrogen can slow down or stop the growth of some breast cancers that need estrogen to grow. It is used in postmenopausal women for the adjuvant treatment of early breast cancer, for extended adjuvant therapy after 5 years of tamoxifen, and for the treatment of advanced breast cancer. May 29, 2022. Clinical particulars. The enthusiasm over letrozole’s potential grew even more following the completion of a successful in-house phase 1 study in healthy male volunteers, which used a letrozole solution instead of tablets in order to speed up the development process . The primary benefit of using Letrozole is that it can increase the chances of ovulation and pregnancy. S. When the enzyme. Priming utilizes low dose FSH several days before oocyte retrieval and/or uses hCG 36 to 38 hours before. Symptoms of a mild allergic reaction can include: skin rash. 8) 4 (19. The median overall survival was nearly 64 months in. weight gain*. It’s prescribed for adult females*. Instead, the Body Fat, using a Protein called Aromatase, produce it. It is used for: Ovulation induction. 2) First and second-line treatment of. Letrozole is a third-generation aromatase inhibitor, a medication initially developed for its ability to decrease circulating estrogen levels in postmenopausal breast cancer patients. It can also be given as a sequential treatment; 2 years of Letrozole followed by 3 years of tamoxifen. When used as a. Know uses, side effects, dosage, contraindications, substitutes, benefit,. It is on the World. 32% of reviewers reported a positive experience, while 34% reported a negative experience. PMS-Letrozole. Introduction. The growth of breast tumors is often stimulated by the female sex hormone estrogen . You usually take letrozole once a day – try. Femara is indicated for the extended adjuvant treatment of early breast cancer in postmenopausal women, who have received 5 years of adjuvant. Not able to sleep. There is no evidence that the exposure of the oocytes to letrozole increases congenital defects at birth. They’re commonly prescribed for people with polycystic ovary syndrome (PCOS) or unexplained infertility. Breast cancer, early (adjuvant treatment): Females: Postmenopausal: Oral: 2. By decreasing the amount of estrogen in the body, letrozole can slow or stop. Letrozole also enhances intrafollicular androgen. as a fertility treatment if you have polycystic ovary syndrome. Try to avoid alcohol, caffeine, or smoking, because they can worsen these symptoms. It is also used off-label for the treatment of infertility, idiopathic short stature in. 2. Letrozole blocks the synthesis of estrogen in ovarian granulosa cells, resulting in reduced levels of circulating and intraovarian estrogens and increased levels of intraovarian androgens (Velasco and. Femara (letrozole) is a brand-name prescription drug used for certain types of breast cancer. 1) Extended adjuvant treatment of postmenopausal women with early breast cancer who have received prior standard adjuvant tamoxifen therapy. ) [1] . Letrozole was developed after Arimidex but before Aromasin, and it is the strongest and most potent of the three aromatase inhibitors by far. 5mg 2. 4). The first treatment for early stage breast cancer is usually surgery. 0 tablets) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg. 100). Medical information for PMS-Letrozole including its dosage, uses, side, effects, interactions, pictures and warnings. Letrozole is used to treat certain types of breast cancer in women who have already stopped menstruating (postmenopausal). music therapy. Letrozole-induced cycles had improved clinical pregnancy and live birth rates after FETs, compared to artificial and gonadotropin-based ovarian stimulation cycles [14–16]. Decreased breast cancer risks. Buch‐Larsen K, Lund‐Jacobsen T, Andersson M, Schwarz P. My follicles showed zero progress at 12mm so doc had me up my dosage to 5mg of Letrozole (thankfully without having to re-start my cycle). Letrozole lowers the levels of the female sex hormone oestrogen in the body. Results of a safety study to evaluate safety in the adjuvant setting comparing the effect on lumbar spine (L2-L4) BMD of adjuvant treatment with letrozole to that with tamoxifen showed at 24 months a median. Letrozole is also used to help prevent the cancer from returning. 5 MG. It is a hormonal (or "endocrine") treatment for breast cancer. 5mg Tablet belongs to the therapeutic classification of Cytotoxic Chemotherapy Drugs. Letrozole was developed after Arimidex but before Aromasin, and it is the strongest and most potent of the three aromatase inhibitors by far. SPSS19. increased cholesterol in your. 5 milligrams (MG) dosages. 1 The Study of Letrozole Extension (SOLE) study compared intermittent (3. Results of a safety study to evaluate safety in the adjuvant setting comparing the effect on lumbar spine (L2 to L4) BMD of adjuvant treatment with letrozole to that with tamoxifen showed at 24 months a. 17 extended-adjuvant trial, 5 postmenopausal women who were randomised to five years of letrozole or placebo after five years of tamoxifen reported a worsening in mean change scores for. We undertook a retrospective review of over 900 treatment cycles using letrozole in doses. A person may want to expand their understanding of Letrozole uses or Letrozole tablet uses. Weight gain or loss. Day 17 (Lønning et al. Lesbian-specific success rates for each treatment are explained along with risks. Drug Images What is letrozole? If you have a certain type of breast cancer, your doctor may prescribe letrozole oral tablets for you. Brand name: Femara Drug class: - Aromatase Inhibitors VA class: AN900 Chemical name: 4,4′-(1H-1,2,4-triazol-1-ylmethylene)bis-benzonitrile Molecular formula: C 17 H 11 N 5 CAS number: 112809-51-5 Medically reviewed by Drugs.